Based in Vienna, this season Louisa Muller directs at LA Opera, Lyric Opera of Chicago, Boston Baroque, Opera Colorado, and The Juilliard School, as well as reviving her acclaimed The Turn of the Screw for Garsington Opera, which won a 2020 Royal Philharmonic Society Award and was named by The Guardian as one of the Top 10 classical events of the year. She was a finalist for the 2020 International Opera Awards in the Best Newcomer category.

She has directed at the Metropolitan Opera, Grand Théâtre de Genève, Houston Grand Opera, New York Philharmonic, Edinburgh International Festival, Minnesota Opera, Santa Fe Opera, Wolf Trap Opera, and Opera Queensland.

Louisa is featured in the March 2021 issue of Opera News.